Found 52 of ic50 data for polymerid = 6652 
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human NEK1 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 18.4nMAssay Description:Inhibition of human NEK1 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMT: 2°CAssay Description:Inhibition of NEK1 after 1 hr at room temperature by caliper methodMore data for this Ligand-Target Pair
Affinity DataIC50: 433nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human NEK1 using MBP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Inhibition of human NEK1 using myelin basic protein as substrate assessed as residual activity in presence of [gamma-33P]-ATP by radiometric hotspot ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NEK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMT: 2°CAssay Description:Inhibition of NEK1 after 1 hr at room temperature by caliper methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild-type human partial length NEK1 (M1 to K278 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild-type human partial length NEK1 (M1 to K278 residues) expressed in bacterial expression system after 1 hr by Z-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human NEK1 (1 to 505 residues) using RLGRDKYKTLRQI as substrate measured after 40 mins in presence of [gamma33P]ATP by radi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) after 60 mins by z'-lyte kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of human NEK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.25E+4nMT: 2°CAssay Description:Inhibition of NEK1 after 1 hr at room temperature by caliper methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assayMore data for this Ligand-Target Pair
